Ultra-Low-Noise Mixed-Signal VLSI Front-End Design for Biomedical and Sensor Interface Applications

Abstract

Biomedical signal acquisition Systems Biomedical signal acquisition systems work in the microvolt (μV) range, and thus, they are highly prone to noise, interference, and signal distortion that greatly impairs signal fidelity and diagnostic accuracy. To overcome these issues, this paper proposes an ultra-low-noise mixed-signal VLSI front-end architecture particularly designed to surface in biomedical and sensor interface applications. The suggested design incorporates a low-noise amplifier, optimized analog filtering stage, and an efficient mixed-signal interface, including advanced noise reduction methods, and multi objective optimization approaches. Focus is made on reducing the contribution of input referred noise and low power consumption and high signal integrity are maintained. The
simulation outcomes reveal a remarkable decrease in the input-related noises, a high-level of Noise Efficiency Factor (NEF), and an increase in the overall energy efficiency in comparison with traditional models. The proposed front-end is designed to provide a trade-off between bandwidth, noise performance and power consumption rendering the device most suitable in resource-constrained environments. The design is particularly suitable to next-generation wearable health devices, implantable biomedical devices, and wireless body networks due to its compact, low power, and high-fidelity properties.