A Low Noise Potential Divider Based Instrumentation Amplifier for Biomedical Retina Application

Abstract

A potential divider-based instrumentation amplifier with a high CMRR and low noise is intended for use in biomedical applications. The goal of the suggested solution is to accurately remove the 10-bit DAC’s high noise level. The 10-bit DAC has a power dissipation of 4.2µW and an open-loop gain of 52.65dB. Its sampling speed is 10MS/s, and its measured noise is 27.4920µv/√Hz. The suggested bio-potential instrumentation amplifier reduces the noise and power trade-off and boosts the output signal voltage by serving as a sensor interface to enhance electrical activity within the retina. The simulation results show a minimum of 133.0563nv/Hz at 1-50Hz and a maximum of 181nv/Hz with output noise; it is based on a 180nm CMOS process. With a power supply rejection ratio of 89.9dB, a slew rate of 9v/ µs, and an amplifier power usage of 2.896µW at a Vdd of 1.8 v, it is far more suitable to stimulate the remaining retinal neurons.